Myeloid gDNA reference standard

Genomic investigations of myeloid leukemia have demonstrated that several genes are recurrently mutated, leading to new genomic classifications, predictive biomarkers, and new therapeutic targets. Genewell developed myeloid mutation gDNA reference standards covers pathogenic variants, as well as internal tandem duplication (FLT3-IDT). It is a highly complex reference standard including 22 mutations in 19 genes, and covering a wide range of allelic frequencies from 5% to 60%. It is a cost efficiency quality control material for performance validation, assay development and routine QC. Moreover, with a great consistency between NGS and PCR assays platforms, it is also ideal to be used for platform comparison and parallel testings.